Marta Magri during her Master’s project in the Casares’ lab was interested in the genetic regulation that drives the subdivision of the Drosophila head.
The development of the dorsal head is a process tightly regulated. Marta focused on studying the role of wingless (wg) signalling in this mechanism.
The work recently published describes that loss of wg signalling transforms the dorsal/medial head into lateral head structures, including the development of ectopic Compound Eyes (CEs).
On the left image, the Drosphila head showing the compound eye (red color) and ocelli (purple color). On the right image, the loss of function of the wg pathway lead to the formation of an ectopic eye (orange color).
The full work was published in The Royal Society journal, and you can check it:
Marta Magri and Fernando Casares, authors of the paper currently working at the CABD.
Marta Magri is now a PhD student in the Gomez-Skarmeta’s lab.